Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name BALR-2
   Synonyms NA
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name B cell acute lymphoblastic leukemia
   ICD-0-3  M9826/3
   Methods microarray, qPCR etc.
   Sample blood (mononuclear cells)
   Expression Pattern up-regulated
   Function Description

Importantly, high expression of BALR-2 correlated with poor overall survival and diminished response to prednisone treatment. BALR-2 plays a functional role in the pathogenesis and/or clinical responsiveness of B-ALL and that altering the levels of particular lncRNAs may provide a future diretcion for therapeutic development.

   Pubmed ID 25681502
   Year 2015
   Title LncRNA Expression Discriminates Karyotype and Predicts Survival in B-lymphoblastic Leukemia.
   External Links
   Links for  BALR-2 GenBank       HGNC       lncrnadb       Noncode
   Links for  B cell acute lymphoblastic leukemia Omim       Cosmic

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