Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name NEAT1
   Synonyms NEAT1, LINC00084, NCRNA00084, TncRNA, VINC, TncRNA, MENepsilon/beta
   Region GRCh38_11:65422774-65445540    Sequence
   Ensembl ENSG00000245532
   RefSeq NR_028272
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name esophageal squamous cell cancer
   ICD-0-3  
   Methods qPCR, RNAi etc.
   Sample ESCC tissues, cell lines (SHEE, SHEEC)
   Expression Pattern up-regulated
   Function Description

We found that the expression of NEAT1 was higher in ESCC tissues and cells compared with the normal counterparts. Pearson analysis showed that elevated NEAT1 levels were extraordinarily correlated with the tumor size, lymph node metastasis and clinical stage.

   Pubmed ID 26609486
   Year 2015
   Title Up regulation of the long non-coding RNA NEAT1 promotes esophageal squamous cell carcinoma cell progression and correlates with poor prognosis.
   External Links
   Links for  NEAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  esophageal squamous cell cancer Omim       Cosmic

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