Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name NEAT1
   Synonyms NEAT1, LINC00084, NCRNA00084, TncRNA, VINC, TncRNA, MENepsilon/beta
   Region GRCh38_11:65422774-65445540    Sequence
   Ensembl ENSG00000245532
   RefSeq NR_028272
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods qPCR etc.
   Sample HCC tissues
   Expression Pattern up-regulated
   Function Description

Our results revealed that NEAT1 appeared to have higher expression in the HCC tissues, compared with the adjacent non-cancerous liver tissues. High levels of NEAT1 promoted the clinical features of HCC, including the number of tumor nodes, metastasis, clinical TNM stage, the status of portal vein tumor embolus, vaso-invasion and the infiltration of tumor cells. Additionally, high NEAT1 expression levels were significantly associated with the expression level of MDTH, NM23 and MALAT1

   Pubmed ID 26191242
   Year 2015
   Title Clinical implication of long non-coding RNA NEAT1 expression in hepatocellular carcinoma patients
   External Links
   Links for  NEAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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