Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name NEAT1
   Synonyms NEAT1, LINC00084, NCRNA00084, TncRNA, VINC, TncRNA, MENepsilon/beta
   Region GRCh38_11:65422774-65445540    Sequence
   Ensembl ENSG00000245532
   RefSeq NR_028272
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name ovarian cancer
   ICD-0-3 C56.9  
   Methods qPCR, western blot etc.
   Sample ovarian cancer tissues, cell lines (ES2 and SKOV3)
   Expression Pattern up-regulated
   Function Description

We demonstrated that NEAT1 was upregulated in OC tissue specimens and cell lines. In summary, the findings of this study revealed that NEAT1 promoted OC cellsā?? metastasis through regulating the miR-382-3p/ROCK1 axial.

   Pubmed ID 29790629
   Year 2018
   Title Long non-coding RNA NEAT1 promoted ovarian cancer cells' metastasis through regulation of miR-382-3p/ROCK1 axial
   External Links
   Links for  NEAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  ovarian cancer Omim       Cosmic

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