Detail
| LncRNA Name | NEAT1 |
| Synonyms | NEAT1, LINC00084, NCRNA00084, TncRNA, VINC, TncRNA, MENepsilon/beta |
| Region | GRCh38_11:65422774-65445540 Sequence |
| Ensembl | ENSG00000245532 |
| RefSeq | NR_028272 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 M8170/3 |
| Methods | qPCR, Western blot, RIP etc. |
| Sample | cell lines (Hep3B, LM3, MHCC97L, SK-hep1, HepG2, LO2, and HEK-293T ) |
| Expression Pattern | up-regulated |
| Function Description | Taken these together, we speculated that NEAT1 can modulate TGF-B1 expression by sponging hsa-mir-139-5p in HCC. These data indicates that targeting the NEAT1/hsamir-139-5p/TGF-B1 axis could be a new strategy for HCC |
| Pubmed ID | 29797561 |
| Year | 2018 |
| Title | NEAT1 upregulates TGF-B1 to induce hepatocellular carcinoma progression by sponging hsa-mir-139-5p |
| External Links |
| Links for NEAT1 | GenBank HGNC lncrnadb Noncode |
| Links for hepatocellular carcinoma | Omim Cosmic |
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