Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name BANCR
   Synonyms BANCR, LINC00586
   Region GRCh38_9:69296682-69311111    Sequence
   Ensembl ENSG00000278910
   RefSeq NR_047671
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR,Western blot, in vitro knockdown etc.
   Sample cell line (MCF-7, MDA-MB-231, SKBR3, BT-20), breast cancer tissue
   Expression Pattern up-regulated
   Function Description

LncRNA BANCR is highly expressed in breast cancer, which is significantly correlated with the prognosis of patients; moreover, it can promote the growth, invasion and metastasis of ovarian cancer cells. The down-regulation of BANCR can inhibit the proliferation, invasion and metastasis capacities of MCF-7 cells.

   Pubmed ID 29565494
   Year 2018
   Title Long non-coding RNA BANCR indicates poor prognosis for breast cancer and promotes cell proliferation and invasion.
   External Links
   Links for  BANCR GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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