Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name NR_028494
   Synonyms LYRM2, DJ122O8.2
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name papillary thyroid cancer
   ICD-0-3  M8260/3
   Methods microarray, qPCR etc.
   Sample blood
   Expression Pattern down-regulated
   Function Description

Compared with 131I-avid lung metastases, we discovered that two lncRNAs (ENST00000462717 and ENST00000415582) were upregulated and two (TCONS_00024700 and NR_028494) were downregulated in the non-131I-avid lung metastases of PTC. Low (ENST00000462717 and ENST00000415582) and high plasma lncRNA levels(TCONS_00024700and NR_028494) were also found to be associated with better prognosis of PTC patients with lung metastases.

   Pubmed ID 27997908
   Year 2016
   Title Circulating Long Non-Coding RNAs Act as Biomarkers for Predicting 131I Uptake and Mortality in Papillary Thyroid Cancer Patients with Lung Metastases.
   External Links
   Links for  NR_028494 GenBank       HGNC       lncrnadb       Noncode
   Links for  papillary thyroid cancer Omim       Cosmic

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