Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name NR_029373
   Synonyms LEF1-AS1, LEF1NAT
   Region GRCh38_4:108167525-108256836    Sequence
   Ensembl ENSG00000232021
   RefSeq NR_029373
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods microarray, qPCR etc.
   Sample CRC tissues
   Expression Pattern down-regulated
   Function Description

The expression of all 18 candidate lncRNAs was evaluated by RT-qPCR, using 80 pairs of CRC and control tissue samples. Among these, eight lncRNAs (MALAT-1, NR_029373, NR_046321, NR_034119, GAS5, BANCR, NR_026817 and PCAT-1) were found significantly dysregulated in CRC tumor tissues compared with controls.

   Pubmed ID 27591862
   Year 2016
   Title Identification of long noncoding RNAs as potential novel diagnosis and prognosis biomarkers in colorectal cancer.
   External Links
   Links for  NR_029373 GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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