Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name NR_040001
   Synonyms LINC01116, TALNEC2
   Region GRCh38_2:176629589-176637931    Sequence
   Ensembl ENSG00000163364
   RefSeq NR_040001
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name glioma
   ICD-0-3  M9380/3
   Methods qPCR, Western blot etc.
   Sample cell lines (A172, U87)
   Expression Pattern up-regulated
   Function Description

TALNEC2 was highly expressed in GBM with poor prognosis, in GBM specimens derived from short-term survivors and in glioma cells and glioma stem cells.Two of the downregulated miRNAs,miR-21 and miR-191, mediated some of TALNEC2 effects on the stemness and mesenchymal transformation of GSCs.

   Pubmed ID 28423669
   Year 2017
   Title The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells
   External Links
   Links for  NR_040001 GenBank       HGNC       lncrnadb       Noncode
   Links for  glioma Omim       Cosmic

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