Detail
| LncRNA Name | NR2F1-AS1 |
| Synonyms | FLJ42709 |
| Region | GRCh38_5:93409359-93585648 Sequence |
| Ensembl | ENSG00000237187 |
| RefSeq | NR_021490 |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✔ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 M8170/3 |
| Methods | qPCR, Microarray, Western blot etc. |
| Sample | cell lines (Huh7, HepG2, Lo-2), HCC tissues |
| Expression Pattern | up-regulated |
| Function Description | miR-363 targeted the 3'-UTR of NR2F1-AS1 and ABCC1 mRNA,presenting that NR2F1-AS1 promoted ABCC1 expression through endogenous sponging miR-363.NR2F1-AS1 regulates HCC OXA resistance through targeting miR-363-ABCC1 pathway,providing a vital theoretic mechanism and therapeutic target for HCC chemoresistance. |
| Pubmed ID | 29602203 |
| Year | 2018 |
| Title | LncRNA NR2F1-AS1 regulates hepatocellular carcinoma oxaliplatin resistance by targeting ABCC1 via miR-363. |
| External Links |
| Links for NR2F1-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for hepatocellular carcinoma | Omim Cosmic |
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