Detail
| LncRNA Name | PANDAR |
| Synonyms | PANDAR, PANDA |
| Region | GRCh38_6:36673621-36675126 Sequence |
| Ensembl | ENSG00000281450 |
| RefSeq | NR_109836 |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, RNAi, Western blot, Cell proliferation assay etc. |
| Sample | CRC tissues, cell lines (DLD-1, SW620, and HCT116) |
| Expression Pattern | up-regulated |
| Function Description | Expression of PANDAR was increased in curcumin-treated CRC cells. Furthermore, silencing PANDAR in curcumin-treated cells increased apoptosis and greatly attenuated senescence possibly by stimulating the expression of PUMA. |
| Pubmed ID | 28176943 |
| Year | 2017 |
| Title | Silence of long noncoding RNA PANDAR switches low-dose curcumin-induced senescence to apoptosis in colorectal cancer cells. |
| External Links |
| Links for PANDAR | GenBank HGNC lncrnadb Noncode |
| Links for colorectal cancer | Omim Cosmic |
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