Detail
| LncRNA Name | BANCR |
| Synonyms | BANCR, LINC00586 |
| Region | GRCh38_9:69296682-69311111 Sequence |
| Ensembl | ENSG00000278910 |
| RefSeq | NR_047671 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | papillary thyroid cancer |
| ICD-0-3 | M8260/3 |
| Methods | qPCR,Western blot, in vitro knockdown etc. |
| Sample | cells lines(NPA, BCPAP,TPC1,Nthy-ori3-1),PTC tissues |
| Expression Pattern | down-regulated |
| Function Description | BANCR was significantly correlated with lymph node metastasis.BANCR inhibited cancer cell proliferation and invasion, which was associated with the induction of cell-cycle G2/M phase arrest and increased apoptosis. BANCR-mediated PTC cell proliferation and migration. BANCR functions as a tumor suppressor during thyroid carcinogenesis. |
| Pubmed ID | 29675113 |
| Year | 2018 |
| Title | Downregulation of BANCR Promotes Aggressiveness in Papillary Thyroid Cancer via the MAPK and PI3K Pathways. |
| External Links |
| Links for BANCR | GenBank HGNC lncrnadb Noncode |
| Links for papillary thyroid cancer | Omim Cosmic |
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