Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PCA3
   Synonyms PCA3, DD3, NCRNA00019, PCAT3
   Region GRCh38_9:76691980-76863307    Sequence
   Ensembl ENSG00000225937
   RefSeq NR_015342
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name prostate cancer
   ICD-0-3 C61.9  
   Methods PROGENSA PCA3 assay etc.
   Sample blood, urine
   Expression Pattern up-regulated
   Function Description

A PCA3 score threshold of 20 may have the highest utility for seletcing men with clinically insignificant prostate cancer in whom active surveillance may be appropriate; a PCA3 score threshold of 50 may be used to identify men at high risk of harbouring significant prostate cancer who are candidates for RP.

   Pubmed ID 21883822
   Year 2012
   Title The relationship between Prostate CAncer gene 3 (PCA3) and prostate cancer significance.
   External Links
   Links for  PCA3 GenBank       HGNC       lncrnadb       Noncode
   Links for  prostate cancer Omim       Cosmic

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