Detail
| LncRNA Name | PCA3 |
| Synonyms | PCA3, DD3, NCRNA00019, PCAT3 |
| Region | GRCh38_9:76691980-76863307 Sequence |
| Ensembl | ENSG00000225937 |
| RefSeq | NR_015342 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✔ |
| Methylation | ✘ |
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | Northern blot etc. |
| Sample | prostate cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | Differential display code 3 (DD3(PCA3)) is a novel gene with characteristics that indicate its potentially valuable role in early identification of malignancy and in the construction of interventions directed specifically toward malignantly transformed cells. DD3(PCA3) has a messenger RNA product that is highly overexpressed in tumors. Compared with other genetic markers that are associated with prostate tissue, DD3(PCA3) is the most specific marker for malignant disease. |
| Pubmed ID | 14607216 |
| Year | 2003 |
| Title | New targets for therapy in prostate cancer: differential display code 3 (DD3(PCA3)), a highly prostate cancer-specific gene. |
| External Links |
| Links for PCA3 | GenBank HGNC lncrnadb Noncode |
| Links for prostate cancer | Omim Cosmic |
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