Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PCAT-1
   Synonyms LPCAT1, AGPAT10, AGPAT9, AYTL2, LPCAT-1, PFAAP3, lpcat, lysoPAFAT, PCAT-1, PCA1
   Region GRCh38_8:126556323-127419050    Sequence
   Ensembl ENSG00000253438
   RefSeq NR_045262
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name bladder cancer
   ICD-0-3 C67  
   Methods qPCR etc.
   Sample bladder cancer cell lines (5637, T24), bladder cancer tissues
   Expression Pattern up-regulated
   Function Description

This study indicates that genetic variants in lncRNA PCAT1 were associated with bladder cancer susceptibility and the SNP rs710886 may act as a potential biomarker for bladder cancer risk.Single nucleotide polymorphisms (SNPs) are the most common genetic variants.f genes. Accumulated evidence hasshownthat plenty of functional SNPs are converged upon lncRNAs and responsible for bladder cancer carcinogenesis [17].

   Pubmed ID 28627442
   Year 2017
   Title The association of rs710886 in lncRNA PCAT1 with bladder cancer risk in a Chinese population.
   External Links
   Links for  PCAT-1 GenBank       HGNC       lncrnadb       Noncode
   Links for  bladder cancer Omim       Cosmic

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