Detail
LncRNA Name | BANCR |
Synonyms | BANCR, LINC00586 |
Region | GRCh38_9:69296682-69311111 Sequence |
Ensembl | ENSG00000278910 |
RefSeq | NR_047671 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | colorectal cancer |
ICD-0-3 | C19.9 |
Methods | qPCR, RNAi, Western blot etc. |
Sample | CRC tissues, cell lines (SW480, HCT116, RQO, HT-29 etc.) |
Expression Pattern | down-regulated |
Function Description | In this study, we show that BANCR expression was significantly down-regulated in colorectal cancer tissues compared with normal tissues, and overexpression of BANCR suppressed colorectal cancer cell growth in vitro and in vivo.Down_regulation of BANCR contributes to theproliferation of colorectal cancer cells,at least in part,through the regulation of p21 protein. |
Pubmed ID | 25928067 |
Year | 2015 |
Title | Downregulated Long Noncoding RNA BANCR Promotes the Proliferation of Colorectal Cancer Cells via Downregualtion of p21 Expression. |
External Links |
Links for BANCR | GenBank HGNC lncrnadb Noncode |
Links for colorectal cancer | Omim Cosmic |
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