Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name BANCR
   Synonyms BANCR, LINC00586
   Region GRCh38_9:69296682-69311111    Sequence
   Ensembl ENSG00000278910
   RefSeq NR_047671
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR, RNAi, Western blot etc.
   Sample CRC tissues, cell lines (SW480, HCT116, RQO, HT-29 etc.)
   Expression Pattern down-regulated
   Function Description

In this study, we show that BANCR expression was significantly down-regulated in colorectal cancer tissues compared with normal tissues, and overexpression of BANCR suppressed colorectal cancer cell growth in vitro and in vivo.Down_regulation of BANCR contributes to theproliferation of colorectal cancer cells,at least in part,through the regulation of p21 protein.

   Pubmed ID 25928067
   Year 2015
   Title Downregulated Long Noncoding RNA BANCR Promotes the Proliferation of Colorectal Cancer Cells via Downregualtion of p21 Expression.
   External Links
   Links for  BANCR GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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