Detail
LncRNA Name | PCAT-1 |
Synonyms | LPCAT1, AGPAT10, AGPAT9, AYTL2, LPCAT-1, PFAAP3, lpcat, lysoPAFAT, PCAT-1, PCA1 |
Region | GRCh38_8:126556323-127419050 Sequence |
Ensembl | ENSG00000253438 |
RefSeq | NR_045262 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | qPCR etc. |
Sample | BC tissues |
Expression Pattern | up-regulated |
Function Description | over-expression of PCAT-1 in 12/47 (25.5%) of tumoral tissues compared with their corresponding ANCTs. PCAT-1 is possibly involved in the pathogenesis of fraction of breast cancers. Future studies are needed to evaluate its precise function in breast cancer.In other words, PCAT-1 has a protective effect on cMyc by disruption of MYC regulation by miR-34a. |
Pubmed ID | 28989584 |
Year | 2017 |
Title | Expression Analysis of Long Non-Coding PCAT-1 in Breast Cancer. |
External Links |
Links for PCAT-1 | GenBank HGNC lncrnadb Noncode |
Links for breast cancer | Omim Cosmic |
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