Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PCAT-1
   Synonyms LPCAT1, AGPAT10, AGPAT9, AYTL2, LPCAT-1, PFAAP3, lpcat, lysoPAFAT, PCAT-1, PCA1
   Region GRCh38_8:126556323-127419050    Sequence
   Ensembl ENSG00000253438
   RefSeq NR_045262
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR etc.
   Sample BC tissues
   Expression Pattern up-regulated
   Function Description

over-expression of PCAT-1 in 12/47 (25.5%) of tumoral tissues compared with their corresponding ANCTs. PCAT-1 is possibly involved in the pathogenesis of fraction of breast cancers. Future studies are needed to evaluate its precise function in breast cancer.In other words, PCAT-1 has a protective effect on cMyc by disruption of MYC regulation by miR-34a.

   Pubmed ID 28989584
   Year 2017
   Title Expression Analysis of Long Non-Coding PCAT-1 in Breast Cancer.
   External Links
   Links for  PCAT-1 GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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