Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PCAT-1
   Synonyms LPCAT1, AGPAT10, AGPAT9, AYTL2, LPCAT-1, PFAAP3, lpcat, lysoPAFAT, PCAT-1, PCA1
   Region GRCh38_8:126556323-127419050    Sequence
   Ensembl ENSG00000253438
   RefSeq NR_045262
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods qPCR
   Sample All cell lines (AGS, Mgastric cancer-803, Bgastric cancer-823, GES-1, MKN-45)
   Expression Pattern up-regulated
   Function Description

Our data suggested that PCAT-1 could play an oncogenic role in gastric cancer progression. Silencing PCAT-1 is a potential novel therapeutic approach for gastric cancer.Over-expression of PCAT-1 was correlated with poor overall survival in gastric cancer patients

   Pubmed ID 28571676
   Year 2017
   Title Long non-coding RNA PCAT-1 over-expression promotes proliferation and metastasis in gastric cancer cells through regulating CDKN1A.
   External Links
   Links for  PCAT-1 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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