Detail
| LncRNA Name | PCAT-14 |
| Synonyms | PCAT14 |
| Region | GRCh38_22:23536881-23547797 Sequence |
| Ensembl | ENSG00000280623 |
| RefSeq | NR_109832 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 M8170/3 |
| Methods | qPCR, Western blot etc. |
| Sample | hepatocellular carcinoma tissues, cell lines (Huh7, HCCLM3, HepG2, SMMC7721, PLC5, and QGY7701) |
| Expression Pattern | up-regulated |
| Function Description | the lncRNA PCAT-14 is overexpressed in patients with hepatocellular carcinoma (HCC), and is associated with a poor prognosis after surgery. In addition, PCAT-14 inhibits miR-372 expression by inducing methylation of the miR-372 promoter. |
| Pubmed ID | 28415780 |
| Year | 2017 |
| Title | Long noncoding RNA PCAT-14 induces proliferation and invasion by hepatocellular carcinoma cells by inducing methylation of miR-372 |
| External Links |
| Links for PCAT-14 | GenBank HGNC lncrnadb Noncode |
| Links for hepatocellular carcinoma | Omim Cosmic |
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