Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PCAT6
   Synonyms PCAT6, KDM5B-AS1, PCAN-R1, ncRNA-a2, onco-lncRNA-96, ncRNA-a2, KDM5BAS1
   Region GRCh38_1:202810962-202811913    Sequence
   Ensembl ENSG00000228288
   RefSeq NR_046325
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name triple negative breast cancer
   ICD-0-3 C50  
   Methods microarray, qPCR etc.
   Sample triple-negative breast cancer tissues
   Expression Pattern up-regulated
   Function Description

We found that the expression levels of TCONS_l2_00003938, ENST00000460164, ENST00000425295, MALAT1 and HOTAIR were significantly higher in tumor tissues than non-tumor tissues, whereas there were no significant differences in the expression levels of the other 3 lncRNAs. Our study identified a set of lncRNAs that were consistently aberrantly expressed in TNBC, and these dysregulated lncRNAs may be involved in the development and/or progression of TNBC.

   Pubmed ID 25996380
   Year 2015
   Title Microarray Expression Profiling of Dysregulated Long Non-Coding RNAs in Triple-Negative Breast Cancer.
   External Links
   Links for  PCAT6 GenBank       HGNC       lncrnadb       Noncode
   Links for  triple negative breast cancer Omim       Cosmic

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