Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PCAT6
   Synonyms PCAT6, KDM5B-AS1, PCAN-R1, ncRNA-a2, onco-lncRNA-96, ncRNA-a2, KDM5BAS1
   Region GRCh38_1:202810954-202812156    Sequence
   Ensembl ENSG00000228288
   RefSeq NR_046325
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name non small cell lung cancer
   ICD-0-3 C34  M8046/3
   Methods qPCR etc.
   Sample NSCLC tissues
   Expression Pattern up-regulated
   Function Description

To identify lncRNAs that are critical to lung carcinogenesis, we selected three lncRNAs, CAR intergenic 10 (hereafter, CAR10), AK311218, and RP11-480I12.3, from the most up-regulated lncRNAs in the HPR NSCLCs (Table S3) and tested their expression by quantitative reverse transcription polymerase chain reaction (qRT-PCR). The expression of these lncRNAs was consistent with the microarray analysis.

   Pubmed ID 27322209
   Year 2016
   Title Long non-coding RNA stabilizes the Y-box-binding protein 1 and regulates the epidermal growth factor receptor to promote lung carcinogenesis.
   External Links
   Links for  PCAT6 GenBank       HGNC       lncrnadb       Noncode
   Links for  non small cell lung cancer Omim       Cosmic

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