Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PCAT6
   Synonyms PCAT6, KDM5B-AS1, PCAN-R1, ncRNA-a2, onco-lncRNA-96, ncRNA-a2, KDM5BAS1
   Region GRCh38_1:202810954-202812156    Sequence
   Ensembl ENSG00000228288
   RefSeq NR_046325
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name prostate cancer
   ICD-0-3 C61.9  
   Methods RNA-seq, microarray, qPCR, RNAi, Northern blot etc.
   Sample prostate cancer tissues, cell lines (LNCaP, CWR22Rv1, PC3 etc.)
   Expression Pattern up-regulated
   Function Description

Both lncRNA showed positive correlation between gene expression and SCNA. The criteria of increasing expression from normal to primary to metastatic prostate cancer aimed to uncover lncRNA that may be important therapeutic targets for both primary and metastatic cancers.

   Pubmed ID 23728290
   Year 2013
   Title Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer.
   External Links
   Links for  PCAT6 GenBank       HGNC       lncrnadb       Noncode
   Links for  prostate cancer Omim       Cosmic

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