Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PCNA-AS1
   Synonyms PCNA-AS1, PCNA-AS, PCNAAS
   Region GRCh38_20:5119586-5119969    Sequence
   Ensembl NA
   RefSeq NR_028370
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods microarray, qPCR etc.
   Sample cell lines (Huh7, SMMC7721)
   Expression Pattern up-regulated
   Function Description

PCNA-AS1 was up-regulated in HCC and its expression status was associated with multiple tumor nodules. The effects of PCNA-AS1 rely on regulation of PCNA via forming RNA hybridization to increase PCNA mRNA stability.

   Pubmed ID 24704293
   Year 2014
   Title Antisense long non-coding RNA PCNA-AS1 promotes tumor growth by regulating proliferating cell nuclear antigen in hepatocellular carcinoma.
   External Links
   Links for  PCNA-AS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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