Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name PEG10
   Synonyms PEG10, EDR, HB-1, MEF3L, 2-Mar, Mart2, RGAG3, RTL2, SIRH1
   Region GRCh38_7:94656325-94669695    Sequence
   Ensembl ENSG00000242265
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name diffuse large B-cell lymphoma
   ICD-0-3  M9680/3
   Methods qPCR, RNAi etc.
   Sample DLBCL tissues, cell lines (OCI-LY-3, OCI-LY-7, OCI-LY-10 etc.)
   Expression Pattern up-regulated
   Function Description

We first found that the expression of PEG10 was upregulated in DLBCL tumorous tissues and that cell lines compared with the normal. Moreover, we illustrated that PEG10 was significantly correlated with B symptoms, IPI score, CHOP-like treatment and rituximab.

   Pubmed ID 25864113
   Year 2015
   Title Upregulation of long noncoding RNA PEG10 associates with poor prognosis in diffuse large B cell lymphoma with facilitating tumorigenicity.
   External Links
   Links for  PEG10 GenBank       HGNC       lncrnadb       Noncode
   Links for  diffuse large B-cell lymphoma Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.