Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PFKFB1
   Synonyms PFKFB1, F6PK, HL2K, PFRX
   Region GRCh38_X:54932961-54998534    Sequence
   Ensembl ENSG00000158571
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods microarray, qPCR, RNAi etc.
   Sample HCC tissues
   Expression Pattern down-regulated
   Function Description

To validate expression of the 6 HH-lncRNAs, qRT-PCR was performed in a cohort of 20 HCC patients, including 10 primary HCC and 10 HBV-related HCC. Expression of 6 HH-lncRNAs validated by qRT-PCR was consistent with microarray results.

   Pubmed ID 27285756
   Year 2016
   Title Comprehensive analysis of long non-coding RNA expression profiles in hepatitis B virus-related hepatocellular carcinoma.
   External Links
   Links for  PFKFB1 GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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