Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PINCR
   Synonyms NA
   Region GRCh38_X:43176994-43226598    Sequence
   Ensembl ENSG00000224294
   RefSeq NR_110387
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR, Western blot, Luciferase reporter assays
   Sample cell lines (HCT116, SW48, RKO, HEK293T)
   Expression Pattern differential expression
   Function Description

Targeted deletion of PINCR in CRC cells significantly impaired G1 arrest and induced hypersensitivity to chemotherapeutic drugs.

   Pubmed ID 28580901
   Year 2017
   Title Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3
   External Links
   Links for  PINCR GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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