Detail
| LncRNA Name | PlncRNA-1 |
| Synonyms | CBR3-AS1, PlncRNA-1, PlncRNA1 |
| Region | GRCh38_21:36131767-36175815 Sequence |
| Ensembl | ENSG00000236830 |
| RefSeq | NR_038892 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR, RNAi, Western blot, Flow cytometry assay etc. |
| Sample | prostate cancer tissues, cell lines (LNCaP, C4-2, DU145, and PC3) |
| Expression Pattern | up-regulated |
| Function Description | PlncRNA-1 expression levels were significantly higher in prostate cancer tissues than in normal prostate tissues. Knockdown of PlncRNA-1 decreases TGF-B1 in LNCaP cells, and overexpression of PlncRNA-1 upregulates TGF-B1 in C4-2 cells. The expression of PlncRNA-1 is related to EMT in prostate cancer. |
| Pubmed ID | 28212533 |
| Year | 2017 |
| Title | Upregulation of long non-coding RNA PlncRNA-1 promotes proliferation and induces epithelial-mesenchymal transition in prostate cancer. |
| External Links |
| Links for PlncRNA-1 | GenBank HGNC lncrnadb Noncode |
| Links for prostate cancer | Omim Cosmic |
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