Detail
LncRNA Name | POU5F1P1 |
Synonyms | POU5F1B, OCT4-PG1, OCT4PG1, OTF3C, OTF3P1, POU5F1P1, POU5F1P4, POU5FLC20, POU5FLC8 |
Region | GRCh38_8:127322183-127420066 Sequence |
Ensembl | ENSG00000212993 |
RefSeq | NA |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✔ |
Methylation | ✘ |
Cancer Name | prostate cancer |
ICD-0-3 | C61.9 |
Methods | qPCR etc. |
Sample | prostate cancer tissues |
Expression Pattern | up-regulated |
Function Description | POU5F1P1 was found to be the only member of the POU5F1 family to be expressed in prostate with over-expression in prostatic carcinoma compared to surrounding prostatic tissue probably because of an increased density of expressing cells. The probability of a positive repeat biopsy increases with rising PCA3 scores. The PCA3 score was superior to %fPSA for predicting repeat prostate biopsy outcome and may be indicative of clinical stage and significance of pCa. |
Pubmed ID | 20017164 |
Year | 2010 |
Title | POU5F1P1, a putative cancer susceptibility gene, is overexpressed in prostatic carcinoma. |
External Links |
Links for POU5F1P1 | GenBank HGNC lncrnadb Noncode |
Links for prostate cancer | Omim Cosmic |
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