Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PRCAT17.3
   Synonyms NA
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name prostate cancer
   ICD-0-3 C61.9  
   Methods qPCR etc.
   Sample prostate cancer tissues, cell line (PC3)
   Expression Pattern up-regulated
   Function Description

Our data revealed that the expression levels of PRCAT17.3 (P<0.0001) and PRCAT38 (P<0.0002) were significantly upregulated in human prostate cancer tissues, compared to BPH ones. Moreover, the altered expression was much higher for PRCAT17.3 (ï½?2000 folds) than PRCAT38 (ï½?50 folds). Moreover, real-time RT-PCR analyses on urine samples of prostate cancer patients revealed that prcat17.3 level is significantly elevated, (P<0.0197; AUC-ROC value of 0.72), compared to that of BPH patients.

   Pubmed ID 29671889
   Year 2018
   Title Two long non-coding RNAs, Prcat17.3 and Prcat38, could efficiently discriminate benign prostate hyperplasia from prostate cancer.
   External Links
   Links for  PRCAT17.3 GenBank       HGNC       lncrnadb       Noncode
   Links for  prostate cancer Omim       Cosmic

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