Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name PRNCR1
   Synonyms PRNCR1, CARLo-3, PCAT8
   Region GRCh38_8:127079874-127092600    Sequence
   Ensembl ENSG00000282961
   RefSeq NR_109833
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR etc.
   Sample CRC tissues
   Expression Pattern differential expression
   Function Description

In overall analyses, we found that the rs13252298 and rs1456315 were associated with significantly decreased risks of CRC. In stratification analyses, we found that CRC patients carrying the rs1456315G were likely to have a tumor size of greater than 5 cm (G vs. A: adjusted OR = 1.56, 95% CI: 1.10-2.23). Additionally, patients with the rs7007694C and rs16901946G had decreased risks to develop poorly differentiated CRC, whereas patients with the rs1456315G had an increased risk to develop poorly differentiated CRC.

   Pubmed ID 24330491
   Year 2013
   Title Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of colorectal cancer.
   External Links
   Links for  PRNCR1 GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.