Detail
| LncRNA Name | PROM1 |
| Synonyms | PROM1, AC133, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4 |
| Region | GRCh38_4:15963076-16084378 Sequence |
| Ensembl | ENSG00000007062 |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | head and neck squamous cell carcinoma |
| ICD-0-3 | C76.0 M8070/3 |
| Methods | microarray, qPCR etc. |
| Sample | blood |
| Expression Pattern | differential expression |
| Function Description | To investigate the role of lncRNAs in HPV16 promoting MDSCs aggregation in HNSCC, we examined 4 lncRNAs (HOTAIR, PROM1, CCAT1 and MUC19) expression in 47 HPV-positive blood samples using qRT-PCR. It turns out that the expression of HOTAIR, PROM1, CCAT1, and MUC19 was negatively associated with the number of MDSCs in HPV-positive HNSCC. |
| Pubmed ID | 28159935 |
| Year | 2017 |
| Title | LncRNAs as an intermediate in HPV16 promoting myeloid-derived suppressor cell recruitment of head and neck squamous cell carcinoma. |
| External Links |
| Links for PROM1 | GenBank HGNC lncrnadb Noncode |
| Links for head and neck squamous cell carcinoma | Omim Cosmic |
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