Detail
LncRNA Name | PTCSC2 |
Synonyms | NA |
Region | GRCh38_9:97805935-97810008 Sequence |
Ensembl | ENSG00000236130 |
RefSeq | NR_147055 |
Circulating | ✔ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | papillary thyroid cancer |
ICD-0-3 | M8260/3 |
Methods | microarray, qPCR etc. |
Sample | PTC tissues, blood |
Expression Pattern | down-regulated |
Function Description | Transcripts of PTCSC2 are down-regulated in PTC tumors. We also observed a significant association of age and CLT with PTCSC2 unspliced transcript levels.Forced expression of PTCSC2 in the BCPAP cell line affected the expression of a subset of non-coding and coding transcripts with enrichment of genes functionally involved in cell cycle and cancer. |
Pubmed ID | 25303483 |
Year | 2014 |
Title | Genetic Predisposition to Papillary Thyroid Carcinoma: Involvement of FOXE1, TSHR, and a Novel lincRNA Gene, PTCSC2. |
External Links |
Links for PTCSC2 | GenBank HGNC lncrnadb Noncode |
Links for papillary thyroid cancer | Omim Cosmic |
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