Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PTENP1
   Synonyms PTENP1, PTEN-rs, PTEN2, PTENpg1, PTH2, psiPTEN
   Region GRCh38_9:33673504-33677499    Sequence
   Ensembl ENSG00000237984
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name clear cell renal cell carcinoma
   ICD-0-3 C64.9  M8005/0
   Methods qPCR etc.
   Sample renal tumour tissues
   Expression Pattern down-regulated
   Function Description

After marker discovery, we used the training set to detect the levels of these promising lncRNAs by RT and quantitative polymerase chain reaction (RT-qPCR) in a cohort of 24 patients with ccRCC and 27 normal controls. Five lncRNAs (lncRNA-LET, PVT1, PANDAR, PTENP1 and linc00963) were significantly downregulated in the serum of patients compared to the healthy controls.

   Pubmed ID 26878386
   Year 2016
   Title A serum-circulating long noncoding RNA signature can discriminate between patients with clear cell renal cell carcinoma and healthy controls.
   External Links
   Links for  PTENP1 GenBank       HGNC       lncrnadb       Noncode
   Links for  clear cell renal cell carcinoma Omim       Cosmic

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