Detail
| LncRNA Name | PTENP1 |
| Synonyms | PTENP1, PTEN-rs, PTEN2, PTENpg1, PTH2, psiPTEN |
| Region | GRCh38_9:33673504-33677499 Sequence |
| Ensembl | ENSG00000237984 |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR, Western blot, Dual-luciferase reporter assay, Cell proliferation assay etc. |
| Sample | cell lines (293T, PC3) |
| Expression Pattern | down-regulated |
| Function Description | We find that PTENP1 is biologically active as it can regulate cellular levels of PTEN and exert a growth-suppressive role. We also show that the PTENP1 locus is selectively lost in human cancer. |
| Pubmed ID | 20577206 |
| Year | 2010 |
| Title | A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. |
| External Links |
| Links for PTENP1 | GenBank HGNC lncrnadb Noncode |
| Links for prostate cancer | Omim Cosmic |
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