Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name PTENP1
   Synonyms PTENP1, PTEN-rs, PTEN2, PTENpg1, PTH2, psiPTEN
   Region GRCh38_9:33673504-33677499    Sequence
   Ensembl ENSG00000237984
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name osteosarcoma
   ICD-0-3  M9180/3
   Methods qPCR, Western blot etc.
   Sample cell lines (Mg63 and SAOS2)
   Expression Pattern differential expression
   Function Description

In conclusion, the results of the present study indicated that lnPTENP1 may inhibit osteosarcoma cell growth via the PI3K/AKT signaling pathway, which may be a potential novel target for human osteosarcoma therapy.

   Pubmed ID 29805503
   Year 2018
   Title Long non-coding RNA phosphatase and tensin homolog pseudogene 1 suppresses osteosarcoma cell growth via the phosphoinositide 3-kinase/protein kinase B signaling pathway
   External Links
   Links for  PTENP1 GenBank       HGNC       lncrnadb       Noncode
   Links for  osteosarcoma Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.