Detail
| LncRNA Name | PTENP1-AS |
| Synonyms | PTENpg1-asRNA |
| Region | GRCh38_9:33677268-33688011 Sequence |
| Ensembl | ENSG00000281128 |
| RefSeq | NR_103745 |
| Circulating | ✔ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, RNAi etc. |
| Sample | cell lines (AGS1, MGC803, SGC7901, and MKN45), gastric adenocarcinomas tissues |
| Expression Pattern | up-regulated |
| Function Description | In the present study, we observed a higher level of H19 which sponged out the low level expressed miR-148a leading to the overexpression of its target mRNA DNMT1. In this study, we observed upregulation of PTENP1-AS increased the EGFR and AGO4 level in tumors. In addition, we also observed that lncRNA GAS5 competes with AGO4 for miR-21. Compared to PTENP1-AS, |
| Pubmed ID | 29719612 |
| Year | 2018 |
| Title | Comprehensive analysis of aberrantly expressed lncRNAs and construction of ceRNA network in gastric cancer. |
| External Links |
| Links for PTENP1-AS | GenBank HGNC lncrnadb Noncode |
| Links for gastric cancer | Omim Cosmic |
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