Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PVT1
   Synonyms PVT1, LINC00079, MYC, NCRNA00079, onco-lncRNA-100, MIR1204HG
   Region GRCh38_8:127794533-128101253    Sequence
   Ensembl ENSG00000249859
   RefSeq NR_003367
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name B-cell lymphoma
   ICD-0-3  M9591/3
   Methods qPCR, FISH, ISH etc.
   Sample bone marrow, lymph node, pleural effusion
   Expression Pattern differential expression
   Function Description

In addition, not only MYC rearrangement but also PVT1 rearrangement may also be implicated in the disease development of HABCLs with 8q24 abnormalities.

   Pubmed ID 23547836
   Year 2013
   Title Deletion or methylation of CDKN2A/2B and PVT1 rearrangement occur frequently in highly aggressive B-cell lymphomas harboring 8q24 abnormality.
   External Links
   Links for  PVT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  B-cell lymphoma Omim       Cosmic

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