Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PVT1
   Synonyms PVT1, LINC00079, MYC, NCRNA00079, onco-lncRNA-100, MIR1204HG
   Region GRCh38_8:127794533-128101253    Sequence
   Ensembl ENSG00000249859
   RefSeq NR_003367
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name renal cell carcinoma
   ICD-0-3 C64.9  
   Methods qPCR
   Sample renal cell carcinoma tissues
   Expression Pattern up-regulated
   Function Description

PVT1 expression was positively associated with gender, tumor size,pT stage, TNM stage, and Fuhrman grade.patients with high PVT1 expression had shorter disease-free survival (DFS) and overall-survival (OS) than those with low PVT1 expression, and multivariate analysis identified PVT1 as an independent prognostic factor in ccRCC.

   Pubmed ID 29081406
   Year 2017
   Title Upregulation of long noncoding RNA PVT1 predicts unfavorable prognosis in patients with clear cell renal cell carcinoma.
   External Links
   Links for  PVT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  renal cell carcinoma Omim       Cosmic

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