Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name BC023629
   Synonyms NA
   Region GRCh38_5:177486968-177488049    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name pancreatic cancer
   ICD-0-3 C25  
   Methods qPCR etc.
   Sample pancreatic cancer tissues, cell lines (Sw1990, PANC-1, BXPC-8 etc.)
   Expression Pattern up-regulated
   Function Description

We further confirmed the selected 6 up-regulation of LncRNAs in PC tissues and PC cell lines through qPCR. Comparing to 293T cells, the expression of LncRNA AF339813 was significantly increased about 10-fold in PANC-1 cells, 8-fold in SW1990 cells and 8.9-fold in BxCP-3 cells. The other 5 LncRNAs have a certain degree of up-regulation in PC cell lines.

   Pubmed ID 26045769
   Year 2015
   Title Downregulation of NUF2 inhibits tumor growth and induces apoptosis by regulating lncRNA AF339813.
   External Links
   Links for  BC023629 GenBank       HGNC       lncrnadb       Noncode
   Links for  pancreatic cancer Omim       Cosmic

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