Detail
| LncRNA Name | PVT1 |
| Synonyms | PVT1, LINC00079, MYC, NCRNA00079, onco-lncRNA-100, MIR1204HG |
| Region | GRCh38_8:127794533-128101253 Sequence |
| Ensembl | ENSG00000249859 |
| RefSeq | NR_003367 |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | malignant pleural mesothelioma |
| ICD-0-3 | M9050/3 |
| Methods | microarray, qPCR, RNAi etc. |
| Sample | MPM tissues, MPM cell lines |
| Expression Pattern | up-regulated |
| Function Description | Our results suggest that C-MYC and PVT1 CNG promotes a malignant phenotype of MPM, with C-MYC CNG stimulating cell proliferation and PVT1 both stimulating proliferation and inhibiting apoptosis. |
| Pubmed ID | 24926545 |
| Year | 2014 |
| Title | Frequent coamplification and cooperation between C-MYC and PVT1 oncogenes promote malignant pleural mesothelioma. |
| External Links |
| Links for PVT1 | GenBank HGNC lncrnadb Noncode |
| Links for malignant pleural mesothelioma | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.