Detail
| LncRNA Name | PVT1 |
| Synonyms | PVT1, LINC00079, MYC, NCRNA00079, onco-lncRNA-100, MIR1204HG |
| Region | GRCh38_8:127794533-128101253 Sequence |
| Ensembl | ENSG00000249859 |
| RefSeq | NR_003367 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | melanoma |
| ICD-0-3 | M8720/3 |
| Methods | qPCR |
| Sample | melanoma tissues, cell lines (M21, B16F10, MM200, MEL-RM, A375, A2058) |
| Expression Pattern | up-regulated |
| Function Description | Expression of PVT1 was significantly up-regulated in melanoma tissue and associated with poor prognosis.Overall,our study demonstrates the oncogenic role of PVT1 as a miR-26b sponge, possibly providing a novel therapeutic target for melanoma |
| Pubmed ID | 28409552 |
| Year | 2017 |
| Title | Long Noncoding RNA PVT1 Promotes Melanoma Progression Via Endogenous Sponging MiR-26b |
| External Links |
| Links for PVT1 | GenBank HGNC lncrnadb Noncode |
| Links for melanoma | Omim Cosmic |
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