Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PVT1
   Synonyms PVT1, LINC00079, MYC, NCRNA00079, onco-lncRNA-100, MIR1204HG
   Region GRCh38_8:127794533-128101253    Sequence
   Ensembl ENSG00000249859
   RefSeq NR_003367
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods qPCR, Western blot, RIP
   Sample cell lines (HepG2, Hep3B, Huh-7, HCCLM9, SK-Hep1, and SMMC-7721)
   Expression Pattern up-regulated
   Function Description

It was determined that plasmacytoma variant translocation 1 was significantly higher, while miR-186-5p was statistically lower in the hepatocellular carcinoma tissues than that in the adjacent normal tissues.

   Pubmed ID 28656879
   Year 2017
   Title Long non-coding RNA PVT1 serves as a competing endogenous RNA for miR-186-5p to promote the tumorigenesis and metastasis of hepatocellular carcinoma
   External Links
   Links for  PVT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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