Detail
| LncRNA Name | PVT1 |
| Synonyms | PVT1, LINC00079, MYC, NCRNA00079, onco-lncRNA-100, MIR1204HG |
| Region | GRCh38_8:127794533-128101253 Sequence |
| Ensembl | ENSG00000249859 |
| RefSeq | NR_003367 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR etc. |
| Sample | pancreatic carcinoma tissues, cell lines (PANC-1, AsPC-1 and HEK 293T) |
| Expression Pattern | up-regulated |
| Function Description | PVT1 functions as an endogenous sponge by competing for miR-448 binding to regulate the miRNA target SERBP1,therefore,promotes the proliferation and migration of PC cells. |
| Pubmed ID | 28657147 |
| Year | 2018 |
| Title | LncRNA-PVT1 promotes pancreatic cancer cells proliferation and migration through acting as a molecular sponge to regulate miR-448. |
| External Links |
| Links for PVT1 | GenBank HGNC lncrnadb Noncode |
| Links for pancreatic cancer | Omim Cosmic |
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