Detail
| LncRNA Name | PVT1 |
| Synonyms | PVT1, LINC00079, MYC, NCRNA00079, onco-lncRNA-100, MIR1204HG |
| Region | GRCh38_8:127794533-128101253 Sequence |
| Ensembl | ENSG00000249859 |
| RefSeq | NR_003367 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✔ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR, Western blot |
| Sample | pancreatic cancer tissues, cell line (PANC-1) |
| Expression Pattern | up-regulated |
| Function Description | It showed that plasmacytoma variant translocation 1 (PVT1) expression was significantly upregulated in pancreatic cancer tissues or cell line compared to normal groups. PVT1 promoted epithelial-mesenchymal transition and cell proliferation and migration through downregulating p21 in pancreatic cancer cells. |
| Pubmed ID | 28355965 |
| Year | 2017 |
| Title | Long Noncoding RNA PVT1 Promotes EMT and Cell Proliferation and Migration Through Downregulating p21 in Pancreatic Cancer Cells |
| External Links |
| Links for PVT1 | GenBank HGNC lncrnadb Noncode |
| Links for pancreatic cancer | Omim Cosmic |
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