Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PVT1
   Synonyms PVT1, LINC00079, MYC, NCRNA00079, onco-lncRNA-100, MIR1204HG
   Region GRCh38_8:127794533-128101253    Sequence
   Ensembl ENSG00000249859
   RefSeq NR_003367
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR
   Sample colorectal cancer tissues, cell lines (SW620 and SW480)
   Expression Pattern up-regulated
   Function Description

he results showed that the PVT1 expression in tumor tissues was higher than that in normal tissues, which was significantly correlated with the expression of c-Myc and three c-Myc regulating genes FUBP1, EZH2, and NPM1 and also correlated with the expression of two other PVT1-associated transcript factors nuclear factor-kB and myocyte-specific enhancer factor 2A.

   Pubmed ID 28381186
   Year 2017
   Title The expression pattern of long non-coding RNA PVT1 in tumor tissues and in extracellular vesicles of colorectal cancer correlates with cancer progression
   External Links
   Links for  PVT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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