Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name PVT1
   Synonyms PVT1, LINC00079, MYC, NCRNA00079, onco-lncRNA-100, MIR1204HG
   Region GRCh38_8:127794533-128101253    Sequence
   Ensembl ENSG00000249859
   RefSeq NR_003367
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods qPCR etc.
   Sample gastric cancer tissues, cell lines (AGS, MKN45, 7901 etc.)
   Expression Pattern up-regulated
   Function Description

All the 8 lncRNAs were then subjected to qPCR validation using 20 pairs of GC and control tissues. Among them, HOTAIR, PVT1, H19, MALAT1, GHET1 and HULC were significantly higher in tumor tissues compared with control tissues.

   Pubmed ID 26096073
   Year 2015
   Title Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancer.
   External Links
   Links for  PVT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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