Detail
LncRNA Name | RMRP |
Synonyms | RMRP, CHH, NME1, RMRPR, RRP2 |
Region | GRCh38_9:35657751-35658018 Sequence |
Ensembl | ENSG00000269900 |
RefSeq | NR_003051 |
Circulating | ✔ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | lung cancer |
ICD-0-3 | C36 |
Methods | qPCR etc. |
Sample | blood |
Expression Pattern | differential expression |
Function Description | The panels of three miRNAs (miRs-21, 210, and 486-5p), two lncRNAs (SNHG1 and RMRP), and two FUTs (FUT8 and POFUT1) have a sensitivity of 81-86% and a specificity of 84-87% for diagnosis of lung cancer. From the seven genes, an integromic plasma signature comprising miR-210, SNHG1, and FUT8 is developed that produces higher sensitivity (95.45%) and specificity (96.97%) compared with the individual biomarker panels (all p<0.05). |
Pubmed ID | 29872497 |
Year | 2018 |
Title | An integromic signature for lung cancer early detection. |
External Links |
Links for RMRP | GenBank HGNC lncrnadb Noncode |
Links for lung cancer | Omim Cosmic |
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