Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name RMRP
   Synonyms RMRP, CHH, NME1, RMRPR, RRP2
   Region GRCh38_9:35657751-35658018    Sequence
   Ensembl ENSG00000269900
   RefSeq NR_003051
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name lung cancer
   ICD-0-3 C36  
   Methods qPCR etc.
   Sample blood
   Expression Pattern differential expression
   Function Description

The panels of three miRNAs (miRs-21, 210, and 486-5p), two lncRNAs (SNHG1 and RMRP), and two FUTs (FUT8 and POFUT1) have a sensitivity of 81-86% and a specificity of 84-87% for diagnosis of lung cancer. From the seven genes, an integromic plasma signature comprising miR-210, SNHG1, and FUT8 is developed that produces higher sensitivity (95.45%) and specificity (96.97%) compared with the individual biomarker panels (all p<0.05).

   Pubmed ID 29872497
   Year 2018
   Title An integromic signature for lung cancer early detection.
   External Links
   Links for  RMRP GenBank       HGNC       lncrnadb       Noncode
   Links for  lung cancer Omim       Cosmic

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