Detail
LncRNA Name | BC040587 |
Synonyms | LINC00901, LSAMP-AS4, TCONS_00005428 |
Region | GRCh38_3:116921431-116932238 Sequence |
Ensembl | ENSG00000242385 |
RefSeq | NR_121607 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | gastric cancer |
ICD-0-3 | C16 |
Methods | microarray, qPCR, RNAi etc. |
Sample | gastric cancer tissues |
Expression Pattern | down-regulated |
Function Description | LncRNA M59227 and 3 mRNAs, PLK1, PTTG1 and VCAN, were overexpressed in GC. In contrast, the expression of 4 lncRNAs, LOC150622, AKR7 L, DQ192290 and BC040587, and 2 mRNAs, DRD5 and GDF5, were downregulated in GC.The results indicated that TUSC7 is a p53-regulated tumour suppressor that acts in part by repressing miR-23b and that TUSC7 may be a key regulatory hub in GC. |
Pubmed ID | 25765901 |
Year | 2015 |
Title | Reciprocal repression between TUSC7 and miR-23b in gastric cancer. |
External Links |
Links for BC040587 | GenBank HGNC lncrnadb Noncode |
Links for gastric cancer | Omim Cosmic |
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