Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name RP11-222K16.2
   Synonyms NA
   Region GRCh38_3:27712910-27714005    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name acute myeloid leukemia
   ICD-0-3  M9861/3
   Methods Microarray, qPCR
   Sample Bone marrow
   Expression Pattern differential expression
   Function Description

RP11-222K16.2 might affect the differentiation of natural killer cells, and promote the immunized evasion of AML by regulating Eomesodermin expression. Analysis of this study revealed that dysregulated lncRNAs and mRNAs in AML vs IDA controls could affect the immune system and hematopoietic cell differentiation.

   Pubmed ID 29220122
   Year 2018
   Title Expression profile analysis of long non-coding RNA in acute myeloid leukemia by microarray and bioinformatics.
   External Links
   Links for  RP11-222K16.2 GenBank       HGNC       lncrnadb       Noncode
   Links for  acute myeloid leukemia Omim       Cosmic

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