Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name RP11-434D9.1
   Synonyms RP11-434D9.1, LOC101928858
   Region GRCh38_5:67379378-67805238    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name triple negative breast cancer
   ICD-0-3 C50  
   Methods microarray, qPCR etc.
   Sample primary breast cancer tissues, cell lines (MDA-MB-231, HCC-1937, MDA-MB-468, MDA-MB-453 etc.)
   Expression Pattern down-regulated
   Function Description

The qRT-PCR results showed that, compared with non-TNBC tissues, C17orf76-AS1 and CTC-338M12.3 were dominantly up-regulated in TNBC tissues; on the other hand, RP11-434D9.1, IGKV, LINC00052, BC016831, RP4-781K5.4, and LOC441242 were obviously down-regulated. However, there are some differences between the lncRNA expression patterns of tissues and cell lines. Briefly, compared with the non-TNBC cell group, only 4 lncRNAs (BC016831, IGKV, LINC00052, and RP11-434D9.1) were down-regulated congruously in all 4 TNBC cells.

   Pubmed ID 26910840
   Year 2016
   Title LncRNAs as new biomarkers to differentiate triple negative breast cancer from non-triple negative breast cancer.
   External Links
   Links for  RP11-434D9.1 GenBank       HGNC       lncrnadb       Noncode
   Links for  triple negative breast cancer Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.